About PI
Primary immunodeficiency, or PI, is a disorder that affects the immune system.

What is PI?
PI occurs when antibodies that help fight infection are reduced or missing from the immune system. Patients with PI are more likely to get infections.
How PI is treated
PI is typically treated by using intravenous immunoglobulin (IVIg), like PANZYGA, to increase antibodies and help patients with PI fight infection. A nurse or other member of your treatment team will administer PANZYGA through an infusion in a vein, which can occur in a hospital, an infusion clinic, or at home.

Steps to help prevent infections
Back to topPrimary immunodeficiencies are passed through the genes. Early detection is important, as is a healthy lifestyle. You may find the healthy living tips below to be helpful.
PANZYGA PI treatment benefits
Back to topIn a clinical study, PANZYGA helped prevent patients with PI from getting serious bacterial infections (SBIs).

- Days missed from work or school
- Approximately 50% of all patients missed at least 1 day of work or school due to infections, with an average of fewer than 4 days per person per year

- Hospitalizations due to infections
- 1 adult patient was hospitalized for 4 days due to an infection
PANZYGA PI side effects
Back to topAdverse events reported in >5% of the 51 patients with PI treated with PANZYGA in a study

The most common side effects of PANZYGA in the PI clinical study were headache, abdominal pain, fever, nausea, sinusitis, fatigue, and bronchitis. Allergic reactions may occur.

PI resources
Back to topLearn more about PI by visiting these helpful websites:
These websites are neither owned nor controlled by Pfizer. Pfizer does not endorse and is not responsible for the content or services of these sites.
Stay informed
Back to topLearn more here. When you have questions, it’s best to talk with your healthcare professional. In addition, please find some frequently asked questions and answers.
Help with managing your condition. PANZYGA offers a variety of downloadable resources with information about treatment, including guides to keep track of your therapy, and more.
All in one place. Pfizer IGuide™ can help you understand your insurance coverage and out-of-pocket costs for your prescribed PANZYGA, as well as identify financial assistance options for which you may be eligible.
Learn more. A free mobile app designed to help support the treatment experience for patients.
Sign up for additional information to help you understand more about PANZYGA and to receive free resources.