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About PI

Primary immunodeficiency, or PI, is a disorder that affects the immune system.

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What is PI?

PI occurs when antibodies that help fight infection are reduced or missing from the immune system. Patients with PI are more likely to get infections.

How PI is treated

PI is typically treated by using intravenous immunoglobulin (IVIg), like PANZYGA, to increase antibodies and help patients with PI fight infection. A nurse or other member of your care team will administer PANZYGA through an infusion in a vein, which can occur in a hospital, an infusion clinic, or at home.

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*Eligible, commercially insured patients may pay as little as $0 for PANZYGA and may receive a maximum benefit of $12,500 per year or the cost of patient’s co-pay in a 12-month period (whichever is less) for claims received by the program. Terms and conditions/eligibility requirements apply. See full terms and conditions at

- Patients must have commercial insurance to be eligible

- Patients are not eligible if they are enrolled in a state or federally funded insurance program